منابع مشابه
Transfusion strategies in postinjury coagulopathy.
PURPOSE OF REVIEW Coagulopathy represents one of the major challenges in the management of the severely injured patient. The present review will attempt to define the current 'optimal' transfusion strategies for the coagulopathic trauma patient and to assess potential weaknesses in the pertinent literature. RECENT FINDINGS Existing limitations in the management of postinjury coagulopathy incl...
متن کاملTransfusion strategies for acute upper gastrointestinal bleeding.
BACKGROUND The hemoglobin threshold for transfusion of red cells in patients with acute gastrointestinal bleeding is controversial. We compared the efficacy and safety of a restrictive transfusion strategy with those of a liberal transfusion strategy. METHODS We enrolled 921 patients with severe acute upper gastrointestinal bleeding and randomly assigned 461 of them to a restrictive strategy ...
متن کاملRestrictive versus liberal transfusion strategies for red blood cell transfusion after hip or knee surgery
BACKGROUND Red blood cell (RBC) transfusions are commonly used in surgical patients, but accompanied by many risks such as metabolic derangement, and allergic and febrile reactions. Indications for transfusion in patients after hip or knee surgery have not been definitively evaluated and remain controversial. We performed a meta-analysis to compare the benefits and harms of restrictive versus l...
متن کاملTransfusion thresholds and other strategies for guiding allogeneic red blood cell transfusion.
BACKGROUND There is considerable uncertainty regarding the optimal haemoglobin threshold for the use of red blood cell (RBC) transfusions in anaemic patients. Blood is a scarce resource, and in some countries, transfusions are less safe than others because of a lack of testing for viral pathogens. Therefore, reducing the number and volume of transfusions would benefit patients. OBJECTIVES The...
متن کاملAn approach to transfusion and hemorrhage in trauma: current perspectives on restrictive transfusion strategies.
Hemorrhagic shock is a leading cause of death in trauma patients. Surgical control of bleeding and fluid resuscitation with both crystalloid and blood products remain the mainstay of therapy for injured patients with bleeding. However, there has been a recent re-evaluation of transfusion practice. Both the fear of transmissible disease and the costs of transfusing blood products have led to inc...
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ژورنال
عنوان ژورنال: Nature Reviews Gastroenterology & Hepatology
سال: 2013
ISSN: 1759-5045,1759-5053
DOI: 10.1038/nrgastro.2013.1